Video and artwork by Leah Bury

The Devlin lab at Harvard Medical School uses strategies from chemical biology to study the human microbiome. Our goal is to control the chemistry of human-associated bacteria in order to understand how the microbiome affects human health and disease. The lab leverages expertise from different fields, including synthetic organic chemistry, molecular biology, microbiology, analytical chemistry, and bioinformatics.

The Devlin lab would be a good fit for students and post-docs with either (1) an organic chemistry background interested in using chemistry to study biological problems or (2) a microbiology or biochemistry background interested in studying the human microbiome. If you are interested, get in touch.

Updates: 

February 2020: Check out our latest paper online at Nature Chemical Biology! [link] We’re also excited to see our paper featured on the cover! Special thanks to Leah Bury for the illustration. [link]

January 2020: We welcome Chelsea Powell to the lab as a new post-doctoral fellow. Welcome, Chelsea! We also welcome two rotation students from the Harvard Chemical Biology PhD program, Gabriel and Farah, who will be joining us for the next few weeks. Also, our second pre-print was posted on BioRxiv, titled “Bariatric surgery reveals a gut-restricted TGR5 agonist that exhibits anti-diabetic effects.” [link]

November 2019: We are also excited to announce that a paper from our collaboration with the Huh lab was published in Nature. [link]

November 2019: The Devlin lab welcomes a new rotation student, Maggie Chen, a first-year graduate student in the Harvard Chemistry & Chemical Biology PhD Program, who will be joining us for the next few weeks. Welcome, Maggie!

September 2019: The Devlin lab welcomes a new rotation student, Sheila Johnson, a first-year graduate student in the Harvard Chemical Biology PhD Program, who will be joining us for the next few months. Welcome, Sheila!

June 2019: Cornell undergraduate Aiden Kolodziej will be joining us for the summer as part of the BCMP Summer Scholars Program. Welcome, Aiden!

May 2019: Our first pre-print was posted on BioRxiv, titled “Development of a Covalent Inhibitor of Gut Bacterial Bile Salt Hydrolases.” [link]

March 2019: Sloan, Lina, and Megan travel to Montreal to attend and present research at the Microbiome Keystone Conference on Chemical Mechanisms and Biological Consequences. And later in the month, Wei Li officially joins the lab!

February 2019: The Devlin lab welcomes a new rotation student, Wei Li, a first-year graduate student in the Harvard Chemistry & Chemical Biology (CCB) PhD program, who will be with us this month.

November 2018: Snehal received the American Heart Association (AHA) Postdoctoral Fellowship! And Sloan was quoted in a Harvard Medical School article titled, “Spurring Innovation,” about the HMS Dean’s Grant will fund our work in collaboration with Jun Huh’s lab.

October 2018: Our lab and our eLife paper [link] received press coverage from the Harvard Magazine.

September 2018: The Devlin lab welcomes a new rotation student, Bailey Schultz, a first-year graduate student in the Harvard Chemical Biology (CB) PhD program, who will be with us for the next few months. 

July 2018: We have a new paper out online in eLife [link]. Press Coverage: HMS News and Research  Science Daily  Harvard Magazine

June 2018: The Devlin lab welcomes Megan McCurry, a graduate student in the Harvard Chemical Biology PhD program.